WNT4 Mouse anti-Human, Clone: 8C5, Bioss

Mouse Monoclonal Antibody

Supplier:  Bioss BSM51380M

Catalog No. 50-197-9856

Description

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.

Specifications

• Antigen: WNT4
• Classification: Monoclonal
• Concentration: 1 μg/mL
• Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
• Gene Accession No.: P56705
• Gene Symbols: Wnt4
• Immunogen: This WNT4 antibody is generated from a mouse immunized with a recombinant protein between 30-351 amino acids from human WNT4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Western Blot
• Clone: 8C5
• Conjugate: Unconjugated
• Gene: Wnt4
• Gene Alias: Protein Wnt-4; SERKAL; signal molecule; UNQ426/PRO864; wingless-related MMTV integration site 4; wingless-type MMTV integration site family member 4; wingless-type MMTV integration site family, member 4; Wnt family member 4; WNT4; Wnt-4
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 54361
• Content And Storage: -20°C
• Form: Liquid