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Invitrogen™ WNT4 Polyclonal Antibody
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Catalog No. PIPA534324
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50 μg
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PIPA534324 50 μg
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Catalog No. PIPA534324 Supplier Invitrogen™ Supplier No. PA534324
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Bovine, Dog, Horse, Pig (100%) Elephant (94%) Opossum (88%).

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WNT4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Wnt4
Gene Accession No. P22724, P56705, Q9QXQ5
Gene Alias protein Wnt-4; SERKAL; signal molecule; UNQ426/PRO864; wingless-related MMTV integration site 4; wingless-type MMTV integration site family member 4; wingless-type MMTV integration site family, member 4; Wnt family member 4; WNT4; Wnt-4
Gene Symbols Wnt4
Host Species Rabbit
Immunogen Synthetic 16 amino acid peptide from internal region of human WNT4.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100071678, 100327037, 100769003, 22417, 54361, 612367, 789600, 84426
Target Species Human, Mouse, Rat, Canine, Monkey, Bovine, Hamster, Pig, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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