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Invitrogen™ WNT4 Polyclonal Antibody
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Catalog No. PIPA547658
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100 μg
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PIPA547658 100 μg
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Catalog No. PIPA547658 Supplier Invitrogen™ Supplier No. PA547658
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Description

Goat Polyclonal Antibody

The antibody has also been shown to recognize a mammalian cell-expressed mouse Wnt-4 protein in Western blots. Reconstitute at 0.2 mg/mL in sterile PBS.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WNT4
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Wnt4
Gene Accession No. P22724
Gene Alias protein Wnt-4; SERKAL; signal molecule; UNQ426/PRO864; wingless-related MMTV integration site 4; wingless-type MMTV integration site family member 4; wingless-type MMTV integration site family, member 4; Wnt family member 4; WNT4; Wnt-4
Gene Symbols Wnt4
Host Species Goat
Immunogen E. coli-derived recombinant mouse Wnt-4 Ile37-Glu76, Arg222-Thr295.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22417
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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