Invitrogen™ WNT6 Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547580

Catalog No. PIPA547580

Description

In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse (rm) Wnt-4, rmWnt-8a, and rmWnt-9b is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.

Specifications

• Antigen: WNT6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WNT6
• Gene Alias: AA409270; Protein Wnt-6; wingless-related MMTV integration site 6; wingless-related MMTV integration site 6 homolog; wingless-type MMTV integration site family member 6; wingless-type MMTV integration site family, member 6; Wnt family member 6; WNT6; Wnt-6
• Host Species: Sheep
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7475
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q9Y6F9
• Gene Symbols: WNT6
• Immunogen: E. coli-derived recombinant human Wnt-6 Met35-Glu75 and Gln238-Arg299.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG