Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. FEPA5144690

Invitrogen™ WRN Polyclonal Antibody
GREENER_CHOICE

Catalog No. FEPA5144690
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
FEPA5144690 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. FEPA5144690 Supplier Invitrogen™ Supplier No. PA5144690
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: LKDKSIRCSN WSKFPLTEDQ KLYAATDAYA GFIIYRNLEI LDDTVQRFAI NKEEEILLSD MNKQLTSISE EVMDLAKHLP HAFSKLENPR RVSILLKDIS ENLYSLRRMI IGSTN Antigen sequence identity: Mouse 66%; Rat 65%.

This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WRN
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene WRN
Gene Accession No. Q14191
Gene Alias AI846146; DKFZp686C2056; DNA helicase, RecQ-like type 3; exonuclease WRN; RecQ protein-like 2; RecQ3; RECQL2; RECQL3; RGD1564788; similar to Werner syndrome helicase homolog; Werner syndrome ATP-dependent helicase; Werner syndrome ATP-dependent helicase homolog; Werner syndrome homolog (human); Werner syndrome RecQ like helicase; Werner syndrome, RecQ helicase-like; WRN
Gene Symbols WRN
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 190-304. Recombinant protein control fragment (Product #RP-110122).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7486
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.