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Invitrogen™ WSB1 Polyclonal Antibody
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Catalog No. PIPA551884
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100 μL
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PIPA551884 100 μL
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Catalog No. PIPA551884 Supplier Invitrogen™ Supplier No. PA551884
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: APFDKKCGRE NWTVAFAPDG SYFAWSQGHR TVKLVPWSQC LQNFLLHGTK NVTNSSSLRL PRQNSDGGQK NKPREHIIDC GDIVWSLAFG SSVPEKQSRC VNIEWHRFRF GQDQLLLATG LNNGRIKIWD V Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.

WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein that contains one SOCS box domain and six WD repeats. Expressed as multiple alternatively spliced isoforms, WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2. Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen WSB1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene WSB1
Gene Accession No. Q9Y6I7
Gene Alias 1110056B13Rik; 2700038M07Rik; SOCS box-containing WD protein SWiP-1; SWIP1; WD repeat and SOCS box containing 1; WD repeat and SOCS box-containing 1; WD repeat and SOCS box-containing protein 1; WD repeat and SOCS box-containing protein 1-like protein; WD-40-repeat-containing protein with a SOCS box 1; WSB1; WSB-1
Gene Symbols WSB1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human WSB1. Recombinant protein control fragment (Product #RP-102067).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26118
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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