Invitrogen™ WSB1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA572859

Catalog No. PIPA572859

Description

WSB1 Polyclonal Antibody for Western Blot, IHC (P), ELISA

WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein that contains one SOCS box domain and six WD repeats. Expressed as multiple alternatively spliced isoforms, WSB1 is thought to function as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex that mediates the ubiquitination and proteasomal degradation of target proteins, such as DIO2. Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role for WSB1 in carcinogenesis.

Specifications

• Antigen: WSB1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WSB1
• Gene Alias: 1110056B13Rik; 2700038M07Rik; SOCS box-containing WD protein SWiP-1; SWIP1; WD repeat and SOCS box containing 1; WD repeat and SOCS box-containing 1; WD repeat and SOCS box-containing protein 1; WD repeat and SOCS box-containing protein 1-like protein; WD-40-repeat-containing protein with a SOCS box 1; WSB1; WSB-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26118
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9Y6I7
• Gene Symbols: WSB1
• Immunogen: WSB1 antibody for a 16 amino acid peptide near the amino terminus of human WSB1. The immunogen is within amino acids 70 - 120 of WSB1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG