WT1 Mouse anti-Human, Clone:5G11A5, Abnova™

Catalog No.	Quantity
89-333-125	100 μg

Catalog No. 89-333-125 Supplier Abnova Corporation Supplier No. MAB16633

Description

Mouse monoclonal antibody raised against recombinant human WT1.

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm′s tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq]

Specifications

• Antigen: WT1
• Applications: ELISA, Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: 5G11A5
• Conjugate: Unconjugated
• Description: Wilms tumor 1
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Flow Cytometry (1:200-1:400)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% sodium azide)
• Gene: WT1
• Gene Alias: GUD, WAGR, WIT-2, WT33
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acid 314-479 of human WT1 from E. coli.
• Quantity: 100 μg
• Gene ID (Entrez): 7490
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1