Invitrogen™ WWP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106453

Catalog No. PIPA5106453

Description

Antibody detects endogenous levels of total WWP1.

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined. [provided by RefSeq].

Specifications

• Antigen: WWP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Wwp1
• Gene Alias: 8030445B08Rik; AIP5; atrophin-1 interacting protein 5; atrophin-1-interacting protein 5; DKFZp434D2111; HECT-type E3 ubiquitin transferase WWP1; hSDRP1; NEDD4-like E3 ubiquitin-protein ligase WWP1; Nedd-4-like ubiquitin-protein ligase; SDRP1; TGIF-interacting ubiquitin ligase 1; Tiul1; Unknown (protein for MGC:129005); WW domain containing E3 ubiquitin protein ligase 1; WW domain-containing protein 1; Wwp1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107568, 11059, 297930
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8BZZ3, Q9H0M0
• Gene Symbols: Wwp1
• Immunogen: A synthesized peptide derived from human WWP1(Accession Q9H0M0), corresponding to amino acid residues R508-C558.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov