Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ WYE 687 dihydrochloride

Tocris Bioscience™ WYE 687 dihydrochloride
GREENER_CHOICE

Catalog No. 428250
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
42-825-0 50 mg
42-8210 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. 42-825-0 Supplier Tocris Bioscience™ Supplier No. 4282/50
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Potent and selective mTOR inhibitor

Potent, ATP-competitive inhibitor of mammalian target of rapamycin (mTOR) (IC50 = 7 nM). Displays selectivity for mTOR over PI 3-Kα (∽100-fold) and PI 3-Kγ (∽500-fold). Inhibits phosphorylation of mTORC1 and mTORC2 substrates including S6K, SGK and Akt; blocks VEGF secretion and HIF-1α expression. Exhibits antiproliferative effects in cancer cell lines through G1 cell cycle arrest and selective apoptosis.

Chemical Identifiers

CAS 1062161-90-3
Molecular Formula C28H32N8O3

Specifications

Quantity 50 mg
Formula Weight 601.53
Purity >98%
Molecular Weight (g/mol) 528.617
Chemical Name or Material WYE 687 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.