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XAB1 Antibody (GPN1/2350), HRP, Novus Biologicals™
SDP

Catalog No. NB009213 Shop All R&D Systems Products
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NB009213 0.1 mL
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Catalog No. NB009213 Supplier Novus Biologicals Supplier No. NBP275783H
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Description

Mouse Monoclonal Antibody

XAB1 Monoclonal specifically detects XAB1 in Human samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen XAB1
Applications Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone GPN1/2350
Conjugate HRP
Dilution Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation PBS with No Preservative
Gene Alias ATP(GTP)-binding protein, ATPBD1A, GPN-loop GTPase 1, GTPase, MBD2-interacting protein, MBDin, MBDINXPA binding protein 1, XAB1FLJ51176, XPA-binding protein 1
Gene Symbols GPN1
Host Species Mouse
Immunogen Recombinant full-length human XAB1 protein (Uniprot: Q9HN4)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Signal Transduction
Primary or Secondary Primary
Test Specificity GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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