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  5. Tocris Bioscience™ XAP 044

Tocris Bioscience™ XAP 044
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Catalog No. 524850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective mGlu7 antagonist

XAP 044 is a potent and selective mGlu7 antagonist (IC50 = 88 nM); inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice. Displays no effects on the LTP of mGlu7 deficient mice. Exhibits novel activity by binding to the mGlu7 Venus flytrap domain (VFTD). Exhibits anti-anxiety effects in rodent models. Brain penetrant.

Specifications

Quantity 50 mg
Product Type XAP 044
Purity >98%
Molecular Weight (g/mol) 380.13
Inhibitors XAP 044

For Research Use Only

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