Invitrogen™ XLF Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596310

Catalog No. PIPA596310

Description

Immunogen sequence: MEELEQGLLM QPWAWLQLAE NSLLAKVFIT KQGYALLVSD LQQVWHEQVD TSVVSQRAKE LNKRLTAPPA AFLCHLDNLL RPLLKDAAHP SEATFSCDCV ADALILRVRS ELSGLPFYWN FHCMLASPSL VSQHLIRPLM GMSLALQCQV RELATLLHMK DLEIQDYQES GATLIRDRLK TEPFEENSFL EQFMIEKLPE ACSIGDGKPF VMNLQDLYMA VTTQEVQVGQ KHQGAGDPHT SNSASLQGID SQCVNQPEQL VSSAPTLSAP EKESTGTSGP LQRPQLSKVK RKKPRGLFS; Positive Samples: Hela, Jurkat; Cellular Location: Nucleus.

Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.

Specifications

• Antigen: XLF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NHEJ1
• Gene Alias: 1700029B21Rik; cernunnos; FLJ12610; Nhej1; non-homologous end joining factor 1; non-homologous end-joining factor 1; nonhomologous end-joining factor 1; protein cernunnos; Xlf; XRCC4-like factor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 363251, 75570, 79840
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Western Blot
• Concentration: 0.49 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q3KNJ2, Q6AYI4, Q9H9Q4
• Gene Symbols: NHEJ1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human NHEJ1 (NP_0790581).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG