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XPA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 164621AP150UL

Description
The XPA (xeroderma pigmentosumgroup A) protein specifically recognizes the UV-orchemically damaged DNA lesions, and triggers thenucleotide excision repair process. XPA binds to thereplication protein A (RPA) or the excision repaircross complementing 1 protein (ERCC 1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a >2000 fold increased risk to develop skin cancer atsun-exposed areas.Specifications
XPA | |
Polyclonal | |
Unconjugated | |
XPA | |
XP1, XPA, XPAC | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
22590, 298074, 7507 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot | |
0.22 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P23025, Q64267 | |
XPA | |
XPA Fusion Protein Ag9536 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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