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XPA Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 164621AP150UL

Encompass_Preferred

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Catalog No. 50-173-0960


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Description

Description

The XPA (xeroderma pigmentosumgroup A) protein specifically recognizes the UV-orchemically damaged DNA lesions, and triggers thenucleotide excision repair process. XPA binds to thereplication protein A (RPA) or the excision repaircross complementing 1 protein (ERCC 1). In the absence of nucleotide excision repair persisting (unrepaired) DNA lesions (adducts) may lead to the accumulation of gene mutations and ultimately to cancer. Xeroderma pigmentosum patients have a >2000 fold increased risk to develop skin cancer atsun-exposed areas.
Specifications

Specifications

XPA
Polyclonal
Unconjugated
XPA
XP1, XPA, XPAC
Rabbit
Antigen Affinity Chromatography
RUO
22590, 298074, 7507
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
0.22 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P23025, Q64267
XPA
XPA Fusion Protein Ag9536
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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