XPC Rabbit anti-Human, Mouse, Rat, Polyclonal, liquid, OriGene

Rabbit Polyclonal Antibody

Supplier:  OriGene TA890156

Catalog No. 50-168-4838

Description

This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: XPC
• Classification: Polyclonal
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P51612, Q01831
• Gene Symbols: Xpc
• Immunogen: Recombit protein of human XPC
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: XPC
• Gene Alias: RAD4, XP3, XPCC, p125
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22591, 312560, 7508
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid