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Invitrogen™ XPD Recombinant Rabbit Monoclonal Antibody (JE55-02)
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Catalog No. PIMA536206
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100 μL
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PIMA536206 100 μL
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Catalog No. PIMA536206 Supplier Invitrogen™ Supplier No. MA536206
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Description

Rabbit Recombinant Monoclonal Antibody

XPD Recombinant Monoclonal Antibody for IHC (P), Western Blot

XPD is involved with the nucleotide excision repair pathway that is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen XPD
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE55-02
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene ERCC2
Gene Accession No. P18074
Gene Alias AA407812; AU020867; AW240756; basic transcription factor 2 80 kDa subunit; BTF2 p80; COFS2; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; EM9; ERCC excision repair 2, TFIIH core complex helicase subunit; Ercc2; Ercc-2; excision repair cross-complementation group 2; excision repair cross-complementing rodent repair deficiency, complementation group 2; General transcription and DNA repair factor IIH helicase subunit XPD; MGC102762; MGC126218; MGC126219; TFIIH; TFIIH 80 kDa subunit; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH basal transcription factor complex helicase subunit; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH basal transcription factor complex helicase XPD subunit; TFIIH p80; TFIIH subunit XPD; TTD; TTD1; xeroderma pigmentosum complementary group D; xeroderma pigmentosum group D-complementing protein; XPD; XPDC
Gene Symbols ERCC2
Host Species Rabbit
Immunogen Recombinant protein within Human XPD aa 620-760.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2068
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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