XRCC1 Monoclonal Antibody (33-2-5), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA513412

Catalog No. PIMA513412

Description

MA5-13412 targets XRCC1 in IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples. The MA5-13412 immunogen is recombinant human XRCC1 protein.

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.

Specifications

• Antigen: XRCC1
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P18887, Q9ESZ0
• Gene Symbols: XRCC1
• Immunogen: Recombinant human XRCC1 protein
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 33-2-5
• Conjugate: Unconjugated
• Gene: XRCC1
• Gene Alias: DNA repair protein XRCC1; RCC; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross complementing 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1; XRCC1; Xrcc-1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 7515, 84495
• Content And Storage: 4° C
• Form: Liquid