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XRCC1 Monoclonal Antibody (33-2-5), Invitrogen™

Catalog No. PIMA513412
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500 μL
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Catalog No. Quantity
PIMA513412 500 μL
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Catalog No. PIMA513412 Supplier Thermo Scientific Supplier No. MA513412

Description

Mouse Monoclonal Antibody

MA5-13412 targets XRCC1 in IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples. The MA5-13412 immunogen is recombinant human XRCC1 protein.

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
TRUSTED_SUSTAINABILITY

Specifications

Antigen XRCC1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 33-2-5
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene XRCC1
Gene Accession No. P18887, Q9ESZ0
Gene Alias DNA repair protein XRCC1; RCC; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross complementing 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1; XRCC1; Xrcc-1
Gene Symbols XRCC1
Host Species Mouse
Immunogen Recombinant human XRCC1 protein
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7515, 84495
Target Species Human, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2b
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