XRCC1 Mouse anti-Human, Clone: OTI2F8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF500880

Catalog No. 50-165-9927

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.

Specifications

• Antigen: XRCC1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: XRCC1
• Gene Alias: RCC, SCAR26
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7515
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2F8
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P18887
• Gene Symbols: XRCC1
• Immunogen: Full length human recombit protein of human XRCC1 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1