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XRCC1 Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993355
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100 μL
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50-199-3355 10 μL
50-199-3354 100 μL
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Catalog No. 50-199-3355 Supplier Active Motif Supplier No. 61372
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Description

Rabbit Polyclonal Antibody

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.

Specifications

Antigen XRCC1
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene XRCC1
Gene Accession No. P18887
Gene Alias DNA repair protein XRCC1; RCC; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross complementing 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1; Xrcc1; Xrcc-1
Gene Symbols XRCC1
Host Species Rabbit
Immunogen This antibody was raised against a recombinant protein corresponding to the N-terminal region of human XRCC1.
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7515
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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