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Invitrogen™ XRCC1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA529359
Description
Recommended positive controls: 293T, A431. Predicted reactivity: Mouse (90%), Rat (90%), Dog (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
Specifications
XRCC1 | |
Polyclonal | |
Unconjugated | |
XRCC1 | |
DNA repair protein XRCC1; RCC; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross complementing 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1; XRCC1; Xrcc-1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
7515, 84495 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.73 mg/mL | |
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
P18887, Q9ESZ0 | |
XRCC1 | |
Recombinant fragment corresponding to a region within amino acids 1 and 281 of Human XRCC1. | |
100 μL | |
Primary | |
Human, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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