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Invitrogen™ XRCC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529359

Catalog No. PIPA529359


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Description

Description

Recommended positive controls: 293T, A431. Predicted reactivity: Mouse (90%), Rat (90%), Dog (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

XRCC1
Polyclonal
Unconjugated
XRCC1
DNA repair protein XRCC1; RCC; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross complementing 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1; XRCC1; Xrcc-1
Rabbit
Antigen Affinity Chromatography
RUO
7515, 84495
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.73 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P18887, Q9ESZ0
XRCC1
Recombinant fragment corresponding to a region within amino acids 1 and 281 of Human XRCC1.
100 μL
Primary
Human, Rat
Antibody
IgG
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