Invitrogen™ XRCC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534707

Catalog No. PIPA534707

Description

Recommended positive controls: Molt-4, Raji. Predicted reactivity: Rat (81%), Bovine (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair.

Specifications

• Antigen: XRCC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: XRCC2
• Gene Alias: 4921524O04Rik; 8030409M04Rik; DKFZp781P0919; DNA repair protein XRCC2; FANCU; RAD51; RecA; recA/RAD51 family protein; RGD1564823; X-ray repair complementing defective repair in Chinese hamster cells 2; X-ray repair cross complementing 2; X-ray repair cross complementing protein 2; X-ray repair cross-complementing protein 2; Xrcc2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7516
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O43543
• Gene Symbols: XRCC2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human XRCC2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov