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Invitrogen™ XRCC3 Polyclonal Antibody
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Catalog No. APPA6535
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100 μL
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APPA6535 100 μL
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Catalog No. APPA6535 Supplier Invitrogen™ Supplier No. PA116535
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Description

Rabbit Polyclonal Antibody

This antibody is specific for XRCC3; no cross-reactivity was observed with XRCC2, RAD51, RAD51B, RAD51C, or RAD51D. This antibody is not recommended for ICC/IF applications. Suggested positive control: antigen standard for XRCC3 (transient overexpression lysate), TK6 lysates and 100 μg HeLa lysates.

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen XRCC3
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene XRCC3
Gene Accession No. O43542
Gene Alias 4432412E01Rik; AI182522; AW537713; CMM6; DNA repair protein XRCC3; DNA repair protein XRCC3-like; LOC102551085; RAD51 like; X-ray repair complementing defective repair in Chinese hamster cells 3; X-ray repair cross complementing 3; X-ray repair cross-complementing protein 3; XRCC 3; XRCC3
Gene Symbols XRCC3
Host Species Rabbit
Immunogen A synthetic partial peptide of human XRCC3.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103161145, 7517
Target Species Human, Hamster, Drosophila
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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