Invitrogen™ XRCC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521280

Catalog No. PIPA521280

Description

Recommended positive controls: human XRCC3-transfected 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.

Specifications

• Antigen: XRCC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: XRCC3
• Gene Alias: 4432412E01Rik; AI182522; AW537713; CMM6; DNA repair protein XRCC3; DNA repair protein XRCC3-like; LOC102551085; RAD51 like; X-ray repair complementing defective repair in Chinese hamster cells 3; X-ray repair cross complementing 3; X-ray repair cross-complementing protein 3; XRCC 3; XRCC3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7517
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O43542
• Gene Symbols: XRCC3
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human XRCC3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG