XRCC4 Mouse anti-Human, Clone: OTI4H9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF500650

Catalog No. 50-165-9717

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants.

Specifications

• Antigen: XRCC4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: XRCC4
• Gene Alias: SSMED
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7518
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4H9
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q13426
• Gene Symbols: XRCC4
• Immunogen: Full-length protein expressed in 293T cell transfected with human XRCC4 expression vector
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1