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XRCC4 Rabbit anti-Human, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501730504 Shop All Proteintech Group Inc Products
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50-173-0504 150 μL
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Catalog No. 50-173-0504 Supplier Proteintech Group Inc Supplier No. 158171AP150UL
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Description

Rabbit Polyclonal Antibody

The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad51. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.

Specifications

Antigen XRCC4
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene XRCC4
Gene Accession No. Q13426
Gene Alias DNA repair protein XRCC4, XRCC4
Gene Symbols Xrcc4
Host Species Rabbit
Immunogen XRCC4 Fusion Protein Ag8606
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 309995, 7518
Target Species Human, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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