Invitrogen™ XRCC6BP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557403

Catalog No. PIPA557403

Description

Immunogen sequence: CEDCNGNVSG GFDASTSQIV LCQNNIHNQA HMNRVVTHEL IHAFDHCRAH VDWFTNIRHL ACSEVRAANL SGDCSLVNEI Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 86%.

The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: XRCC6BP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATP23
• Gene Alias: 1110068E08Rik; 2410012H02Rik; atp23; ATP23 metallopeptidase and ATP synthase assembly factor homolog; Ku70 binding protein 3; Ku70-binding protein 3; KUB3; LOW QUALITY PROTEIN: mitochondrial inner membrane protease ATP23 homolog; mitochondrial inner membrane protease ATP23 homolog; XRCC6 binding protein 1; XRCC6-binding protein 1; Xrcc6bp1; zgc:162885
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 91419
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y6H3
• Gene Symbols: ATP23
• Immunogen: Recombinant protein corresponding to Human XRCC6BP1. Recombinant protein control fragment (Product #RP-95848).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG