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Invitrogen™ XRCC6BP1 Polyclonal Antibody
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Catalog No. PIPA588836
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PIPA588836 100 μL
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Catalog No. PIPA588836 Supplier Invitrogen™ Supplier No. PA588836
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MAGAPDERRR GPAAGEQLQQ QHVSCQVFPE RLAQGNPQQG FFSSFFTSNQ KCQLRLLKTL ETNPYVKLLL DAMKHSGCAV NKDRHFSCED CNGNVSGGFD ASTSQIVLCQ NNIHNQAHMN RVVTHELIHA FDHCRAHVDW FTNIRHLACS EVRAANLSGD CSLVNEIFRL HFGLKQHHQT CVRDRATLSI LAVRNISKEV AKKAVDEVFE SCFNDHEPFG RIPHNKTYAR YAHRDFENRD RYYSNI; Positive Samples: Mouse brain, Rat brain.

The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen XRCC6BP1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene ATP23
Gene Accession No. Q9CWQ3
Gene Alias 1110068E08Rik; 2410012H02Rik; atp23; ATP23 metallopeptidase and ATP synthase assembly factor homolog; Ku70 binding protein 3; Ku70-binding protein 3; KUB3; LOW QUALITY PROTEIN: mitochondrial inner membrane protease ATP23 homolog; mitochondrial inner membrane protease ATP23 homolog; XRCC6 binding protein 1; XRCC6-binding protein 1; Xrcc6bp1; zgc:162885
Gene Symbols ATP23
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_1505921).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 299828, 68876
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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