Invitrogen™ XTP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA131177

Catalog No. PIPA131177

Description

PA1-31177 detects XTP4 from human samples.

During the past decade, the role of the ERBB2(neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505nucleotides from the 3' end of the ERBB2oncogene, the antigenic target for trastuzumab(Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 andERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12-kDa protein of unknown function.

Specifications

• Antigen: XTP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MIEN1
• Gene Alias: 1810046J19Rik; AI463380; C16H17orf37; C17orf37; C35; HBV XAg-transactivated protein 4; HBV X-transactivated gene 4 protein; MGC14832; MIEN1; Migration and invasion enhancer 1; ORB3; protein C17orf37; protein C17orf37 homolog; Protein C35; RDX12; RGD1306682; XTP4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84299
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: tris glycine with 0.5% BSA, 30% glycerol and 0.02% Sodium azide; pH 7.4-7.9
• Gene Accession No.: Q9BRT3
• Gene Symbols: MIEN1
• Immunogen: synthetic peptide EPGQTSVAPPPEEVEPGSC, corresponding to N terminal amino acids 4-21 of Human XTP4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov