Invitrogen™ XYLT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529127

Catalog No. PIPA529127

Description

Recommended positive controls: 293T, A431, HeLa, Raji. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (84%), Japanese Medaka (82%), Dog (98%), Chicken (93%), Chimpanzee (100%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.

Specifications

• Antigen: XYLT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: XYLT2
• Gene Alias: E030002B02Rik; Peptide O-xylosyltransferase 1; peptide O-xylosyltransferase 2; protein xylosyltransferase; protein xylosyltransferase 2; PXYLT2; SOS; UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase; UNQ3058/PRO9878; XT2; XT-II; Xylosyltransferase 2; xylosyltransferase II; Xylt2; xylt-II
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64132
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9H1B5
• Gene Symbols: XYLT2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 272 and 520 of Human Xylosyltransferase II.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov