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Invitrogen™ YAP1 Monoclonal Antibody (1A12)
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Catalog No. PIMA517200
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100 μg
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Catalog No. Quantity
PIMA517200 100 μg
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Catalog No. PIMA517200 Supplier Invitrogen™ Supplier No. MA517200
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Description

Mouse Monoclonal Antibody

MA5-17200 targets YAP1 in indirect ELISA, FACS, IHC, and WB applications and shows reactivity with Human samples. The MA5-17200 immunogen is purified recombinant fragment of human YAP1 expressed in E. Coli.

YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen YAP1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1A12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene YAP1
Gene Accession No. P46937
Gene Alias 65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP
Gene Symbols YAP1
Host Species Mouse
Immunogen Purified recombinant fragment of human YAP1 expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10413
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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