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Invitrogen™ YAP1 Monoclonal Antibody (GT256)
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Catalog No. PIMA527808
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100 μL
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Catalog No. Quantity
PIMA527808 100 μL
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Catalog No. PIMA527808 Supplier Invitrogen™ Supplier No. MA527808
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Description

Mouse Monoclonal Antibody

Positive Control: HeLa, HepG2 Predicted Reactivity: Rat (96%), Zebrafish (87%), Xenopus laevis (81%), Chicken (84%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen YAP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone GT256
Concentration 1.68 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene YAP1
Gene Accession No. P46937, P46938
Gene Alias 65 kDa Yes-associated protein; AI325207; cb194; CH211-181P1.5-001; COB1; Protein yorkie homolog; sb:cb194; si:ch211-181p1.5; si:dkey-3b8.3; transcriptional coactivator YAP1; wu:fc18c04; yap; Yap1; YAP2; Yap65; Yes associated protein 1; Yes1 associated transcriptional regulator; yes-associated protein 1; yes-associated protein 2; yes-associated protein YAP65 homolog; yes-associated protein, 65 kDa; Yki; Yorkie; yorkie homolog; zgc:158380; zYAP
Gene Symbols YAP1
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human YAP1. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10413, 22601
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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