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YAP1 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501562277
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50-156-2277 20 μL
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Catalog No. 50-156-2277 Supplier Bethyl Laboratories, Inc Supplier No. A302308AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway. The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration. Mutations in the IRF5 gene results in coloboma.

Specifications

Antigen YAP1
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene YAP1
Gene Accession No. P46937
Gene Alias YAP, YAP2, YAP65, YKI
Gene Symbols YAP1
Host Species Rabbit
Immunogen Between 250 and 300
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10413
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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