YB1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-156-4600	Bethyl Laboratories, Inc A303230AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predict

YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.

Specifications

• Antigen: YB1
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: Nuclease-sensitive element-binding protein 1; Y-box-binding protein 1; Y-box transcription factor; YB-1; CCAAT-binding; transcription factor I subunit A; CBF-A; Enhancer factor I subunit A; EFI-A; DNA-binding protein B; DBPB; YBX1; NSEP1; YB1
• Immunogen: Between 224 and 274
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: YBX1

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P62960, P67809
• Gene ID (Entrez): 22608, 4904
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody