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YBX1 Monoclonal Antibody (OTI7B4), TrueMAB™, OriGene
SDP

Catalog No. 501680989
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50-168-0989 100 μL
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Catalog No. 50-168-0989 Supplier OriGene Supplier No. TA806164
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Mouse Monoclonal Antibody

YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5′-CTGATTGGCCAA-3′), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.

Specifications

Antigen YBX1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI7B4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene YBX1
Gene Accession No. P67809
Gene Alias BP-8, CBF-A, CSDA2, CSDB, DBPB, EFI-A, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1
Gene Symbols YBX1
Host Species Mouse
Immunogen Full length human recombit protein of human YBX1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4904
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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