Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA580241

Invitrogen™ YBX1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA580241
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA580241 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA580241 Supplier Invitrogen™ Supplier No. PA580241
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human MCF-7 whole cell, human 293T whole cell, human Hela whole cell, human Jurkat whole cell, human T47D whole cell, human THP-1 whole cell, human MOLT4 whole cell, human HL-60 whole cell, rat testis tissue, mouse stomach tissue, mouse testis tissue. IHC: human rectal cancer tissue, human ovarian cancer tissue, mouse testis tissue, rat testis tissue. Flow: HEL cell.

YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
TRUSTED_SUSTAINABILITY

Specifications

Antigen YBX1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene YBX1
Gene Accession No. P62960, P62961, P67809
Gene Alias 1700102N10Rik; BP8; BP-8; Byb1; C79409; Cbfa; CBF-A; CCAAT-binding; CCAAT-binding transcription factor 1 subunit A; CCAAT-binding transcription factor I subunit A; CSDA2; CSDB; dbpB; DNA binding protein B; DNA-binding protein B; EF1A; EFI-A; enhancer factor 1 alpha; enhancer factor 1 subunit A; enhancer factor I subunit A; major histocompatibility complex, class II, Y box-binding protein I; MDR NF1; MDR-NF1; MGC104858; MGC110976; MGC117250; Msy1; Msy-1; mYB-1a; Nsep1; NSEP-1; nuclease sensitive element binding protein 1; nuclease-sensitive element-binding protein 1; Y box binding protein 1; Y box protein 1; Y box transcription factor; YB1; YB-1; Y-box binding protein 1; Y-box transcription factor; Y-box-binding protein 1; YBX1
Gene Symbols YBX1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human YB1 (137-152aa KYAADRNHYRRYPRRR).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22608, 4904, 500538
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.