Invitrogen™ YBX1 Recombinant Rabbit Monoclonal Antibody (10H29L41)

Catalog No.	Quantity
PI702245	100 μg

Catalog No. PI702245 Supplier Invitrogen™ Supplier No. 702245

Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Bovine, Mouse, and Rat. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.

Specifications

• Antigen: YBX1
• Applications: Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 10H29L41
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide; pH 7.2-7.4
• Gene: YBX1
• Gene Accession No.: P67809
• Gene Alias: 1700102N10Rik; BP8; BP-8; Byb1; C79409; Cbfa; CBF-A; CCAAT-binding; CCAAT-binding transcription factor 1 subunit A; CCAAT-binding transcription factor I subunit A; CSDA2; CSDB; dbpB; DNA binding protein B; DNA-binding protein B; EF1A; EFI-A; enhancer factor 1 alpha; enhancer factor 1 subunit A; enhancer factor I subunit A; major histocompatibility complex, class II, Y box-binding protein I; MDR NF1; MDR-NF1; MGC104858; MGC110976; MGC117250; Msy1; Msy-1; mYB-1a; Nsep1; NSEP-1; nuclease sensitive element binding protein 1; nuclease-sensitive element-binding protein 1; Y box binding protein 1; Y box protein 1; Y box transcription factor; YB1; YB-1; Y-box binding protein 1; Y-box transcription factor; Y-box-binding protein 1; YBX1
• Gene Symbols: YBX1
• Host Species: Rabbit
• Immunogen: Peptides corresponding to human YBX1 [1) aa174-aa190 2) aa251-aa270].
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4904
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG