Invitrogen™ Yellow Fever Virus NS3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5112021

Catalog No. PIPA5112021

Description

Yellow Fever Virus NS3 Polyclonal Antibody for Western Blot, ICC/IF

Yellow fever virus (YFV) is an RNA virus belonging to the genus Flavivirus in the family Flaviviridae. YFV measures 40-60 nm in diameter and has a spherical, enveloped structure containing a single-stranded positive-sense RNA genome. The genome encodes three structural proteins (C, prM/M, and E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5). YFV is transmitted by Aedes mosquitoes and is endemic in tropical regions of Africa and South America. It causes yellow fever, a hemorrhagic disease characterized by symptoms such as fever, jaundice, hemorrhage, and organ failure. Pathogenesis involves liver infection leading to hepatocyte and Kupffer cell damage, with the virus utilizing specific genes and molecular mechanisms for neurotropism and viscerotropism.

Specifications

• Antigen: Yellow Fever Virus NS3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Concentration: 2.44 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Yellow Fever Virus NS3 protein (Yellow fever virus (strain 17D vaccine)). The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov