Invitrogen™ Yellow Fever Virus NS5 Polyclonal Antibody

Catalog No.	Quantity
PIPA5112034	100 μL

Catalog No. PIPA5112034 Supplier Invitrogen™ Supplier No. PA5112034

Description

Rabbit Polyclonal Antibody

Yellow Fever Virus NS5 Polyclonal Antibody for Western Blot, ICC/IF

Yellow fever virus (YFV) is an RNA virus belonging to the genus Flavivirus in the family Flaviviridae. YFV measures 40-60 nm in diameter and has a spherical, enveloped structure containing a single-stranded positive-sense RNA genome. The genome encodes three structural proteins (C, prM/M, and E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5). YFV is transmitted by Aedes mosquitoes and is endemic in tropical regions of Africa and South America. It causes yellow fever, a hemorrhagic disease characterized by symptoms such as fever, jaundice, hemorrhage, and organ failure. Pathogenesis involves liver infection leading to hepatocyte and Kupffer cell damage, with the virus utilizing specific genes and molecular mechanisms for neurotropism and viscerotropism.

Specifications

• Antigen: Yellow Fever Virus NS5
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1.62 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of Yellow Fever Virus NS5 protein (Yellow fever virus (strain 17D vaccine)). The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG