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Tocris Bioscience™ Yhhu 3792
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Catalog No. 659910
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65-991-0 10 mg
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Catalog No. 65-991-0 Supplier Tocris Bioscience™ Supplier No. 6599/10
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Description

Notch signaling pathway activator; enhances the self-renewal capability of NSCs; active in vivo

Yhhu 3792 is a notch signaling pathway activator; enhances the self-renewal capability of neural stem cells (NSCs) via Notch signaling pathway activation in vitro and in vivo. Promotes the expression of Notch target genes, Hes3 and Hes5. Expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) after chronic administration in mice. Increases the spatial and episodic memory in mice.

Specifications

Chemical Name or Material 5-(3-Methoxyphenoxy)-N2-[4-(1-methylethyl)phenyl]-2,4-quinazolinediamine hydrochloride
CAS 2624336-93-0
Quantity 10 mg
Target Compounds for NSC Proliferation and Renewal
Molecular Formula C24H24N4O2.HCl
Purity 0.98
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