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Tocris Bioscience™ YM 244769
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Catalog No. 454410
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45-441-0 10 mg
45-445-0 50 mg
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Catalog No. 45-441-0 Supplier Tocris Bioscience™ Supplier No. 4544/10
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Description

Na+/Ca2+ exchange inhibitor (reverse mode); neuroprotective

Inhibitor of the reverse mode of Na+/Ca2+ exchange (NCX). Potently inhibits Na+-dependent 45Ca2+ uptake (IC50 values are 18, 68 and 96 nM for CCL39 cells transfected with NCX3, NCX1 and NCX2 respectively). Displays selectivity for NCX over other Na+ and Ca2+ transporters. Protects against hypoxia/reoxygenation-induced cell damage in neuronal SH-SY5Y cells expressing NCX1 and NCX3.

Chemical Identifiers

CAS 1780390-65-9
Molecular Formula C26H23ClFN3O3

Specifications

Quantity 10 mg
Formula Weight 516.39
Purity >99%
Molecular Weight (g/mol) 479.936
Chemical Name or Material YM 244769

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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