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  5. Tocris Bioscience™ YM 58483

Tocris Bioscience™ YM 58483
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Catalog No. 393910
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Inhibitor of SOCE in non-excitable cells

YM 58483 is a blocker of store-operated Ca2+ entry (SOCE), which mediates the activation of non-excitable cells (e.g. lymphocytes). Inhibits calcium release-activated calcium (CRAC) channels; suppresses thapsigargin -induced sustained Ca2+ influx (IC50 = 100 nM). Displays immuno-modulatory and anti-inflammatory effects; suppresses cytokine production and proliferation of T cells in vitro.

Chemical Identifiers

CAS 223499-30-7
Molecular Formula C15H9F6N5OS

Specifications

Quantity 10 mg
Formula Weight 421.32
Purity >99%
Molecular Weight (g/mol) 421.321
Chemical Name or Material YM 58483

Safety and Handling

Recommended Storage Store at +4°C
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