Invitrogen™ YPEL3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556490

Catalog No. PIPA556490

Description

Immunogen sequence: MVRISKPKTF QAYLDDCHRR YSCAHCRAHL ANHDDLISKS FQGSQGRAYL FNSVVNVGCG PAEERVLLTG LHAVADIHCE NCKTTLGWKY EQAFESSQK Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.

Specifications

• Antigen: YPEL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: YPEL3
• Gene Alias: 0610043B10Rik; 1190001G19Rik; FKSG5; Protein yippee-like 3; RGD1564579; small ubiquitinated apoptotic protein; Suap; yippee like 3; yippee-like 3; yippee-like 3 (Drosophila); YPEL3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 83719
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P61236
• Gene Symbols: YPEL3
• Immunogen: Recombinant protein corresponding to Human YPEL3. Recombinant protein control fragment (Product #RP-101075).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG