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YTHDF2 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 50556390 Shop All Proteintech Group Inc Products
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50-556-390 150 μL
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Catalog No. 50-556-390 Supplier Proteintech Group Inc Supplier No. 247441AP150UL
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Description

Rabbit Polyclonal Antibody

Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation. Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5′-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation.

Specifications

Antigen YTHDF2
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene YTHDF2
Gene Accession No. Q9Y5A9
Gene Alias CLL associated antigen KW 14, HGRG8, NY REN 2, YTH domain family protein 2, YTH domain family, member 2, YTHDF2
Gene Symbols YTHDF2
Host Species Rabbit
Immunogen YTHDF2 Fusion Protein Ag5922
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51441
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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