YWHAZ Mouse anti-Human, Clone: 1B6, Bioss

Catalog No.	Quantity
50-197-9793	100 μL

Catalog No. 50-197-9793 Supplier Bioss Supplier No. BSM51397M

Description

Mouse Monoclonal Antibody

At least seven isoforms comprise the highly conserved 14-3-3 family of homo- and heterodimeric proteins that are abundantly expressed in all eukaryotic cells. Although more than seven isoforms of 14-3-3 have been described, some redundancies have appeared upon sequencing. The 14-3-3s are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. By interacting with Cdc25C, 14-3-3 regulates entry into the cell cycle and through interaction with Bad, prevents apoptosis. Other proteins that have been shown to bind to 14-3-3s include members of the protein kinase C family, Cbl, IRS-1, polyoma middle-T antigen, nitrate reductase, S-raf and the IGF-1 receptor. Detection of 14-3-3 proteins in cerebrospinal fluid has been shown to be useful in the differential diagnosis of Creutzfeldt-Jakob disease and other prion diseases.

Specifications

• Antigen: YWHAZ
• Applications: Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: 1B6
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
• Gene: Ywhaz
• Gene Accession No.: P63104
• Gene Alias: 1110013I11Rik; 14-3-3 delta; 14-3-3 protein zeta/delta; 14-3-3 protein/cytosolic phospholipase A2; 14-3-3 zeta; 1433Z; 14-3-3z; 14-3-3zeta; 14-3-3-zeta; 143Z; AI596267; AL022924; AU020854; BOS_14050; EGM_17526; epididymis luminal protein 4; epididymis secretory protein Li 3; epididymis secretory protein Li 93; Factor activating exoenzyme S; FAS; HEL4; HEL-S-3; HEL-S-93; hypothetical protein; KCIP-1; Mitochondrial import stimulation factor S1 subunit; Msfs1; phospholipase A2; Protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; SEZ-2; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; YWHAD; Ywhaz
• Gene Symbols: Ywhaz
• Host Species: Mouse
• Immunogen: This YWHAZ antibody is generated from a mouse immunized with a recombinant protein from human YWHAZ.
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7534
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b κ