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  5. Tocris Bioscience™ ZAP 180013

Tocris Bioscience™ ZAP 180013
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Catalog No. 682110
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68-211-0 10 mg
68-215-0 50 mg
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Catalog No. 68-211-0 Supplier Tocris Bioscience™ Supplier No. 6821/10
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Description

Zap70 inhibitor; inhibits interaction with ITAMs

ZAP 180013 is a zeta-chain-associated protein kinase 70 (Zap70) inhibitor (IC50 = 1.8 μM in fluorescence polarization assay). Inhibits the interaction of Zap70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs), within the T-cell antigen receptor (TCR) signaling pathway.

Specifications

Chemical Name or Material 5-Chloro-N-[(4-chlorophenyl)methyl]-2-(ethylsulfonyl)-N-(2-furanylmethyl)-4-pyrimidinecarboxamide
CAS 873080-25-2
Quantity 10 mg
Molecular Formula C19H17Cl2N3O4S
Purity 98%
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