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ZBED1 Mouse anti-Human, Clone: OTI1F2, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF505039

Encompass_Preferred

Catalog No. 50-166-3335


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters; anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.
Specifications

Specifications

ZBED1
Monoclonal
Unconjugated
ZBED1
ALTE, DREF, TRAMP, hDREF
Mouse
Affinity Chromatography
RUO
9189
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI1F2
PBS with 8% trehalose and no preservative; pH 7.3
O96006
ZBED1
Full length human recombit protein of human ZBED1 produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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