Invitrogen™ ZBED3 Polyclonal Antibody

Catalog No.	Quantity
PIPA563231	100 μL

Catalog No. PIPA563231 Supplier Invitrogen™ Supplier No. PA563231

Description

Rabbit Polyclonal Antibody

Immunogen sequence: RELQAEREAL QARLRDVSRR EGALGWAPAA PPPLKDDPEG DRDGCVITKV LL Highest antigen sequence identity to the following orthologs: Mouse - 31%, Rat - 40%.

Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.

Specifications

• Antigen: ZBED3
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: ZBED3
• Gene Accession No.: Q96IU2
• Gene Alias: 0610037K01Rik; 2610005H11Rik; AU018975; AU024588; axin-interacting protein; ZBED3; Zinc finger BED domain-containing protein 3; zinc finger BED-type containing 3; zinc finger, BED domain containing 3; zinc finger, BED type containing 3; zinc finger, BED-type containing 3
• Gene Symbols: ZBED3
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human ZBED3. Recombinant protein control fragment (Product #RP-95509).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 84327
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG