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ZBTB10 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501564676
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50-156-4676 20 μL
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Catalog No. 50-156-4676 Supplier Bethyl Laboratories, Inc Supplier No. A303258AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

RINZF is a novel member of the Cys2-His2 zinc finger gene family, having a cDNA sequence of 3.8 kilobases. Apart from the Cys2-His2 zinc finger domains, the RIN ZF coding sequence bears little resemblance to other reported zinc finger genes. The amino-terminal region of the protein is an activation domain, despite the lack of recognizable activation motifs, such as homopolymeric glutamine and proline-rich stretches. Instead, it possesses several regions rich in basic residues, often associated with repressor domains. The gene encoding the RINZF protein is mapped on human chromosome 8q13-q21.1. The protein is highly conserved and acts as a transcriptional regulator. The protein competes with Sp1 binding at the CACC cis-regulatory element of the gastrin promoter and thus has a down-regulatory effect on gastrin transcription. The existence of two transcript variants, isoform 1 and 2, produced by alternate splicing of the RINZF gene has been studied.

Specifications

Antigen ZBTB10
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene ZBTB10
Gene Accession No. Q96DT7
Gene Alias RINZF, zinc finger and BTB domain-containing protein 10, zinc finger protein RIN ZF, zinc finger protein RINZF
Gene Symbols ZBTB10
Host Species Rabbit
Immunogen Between 797 and 847
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 65986
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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