ZBTB10 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A303257A

Catalog No. 50-156-4671

Description

The recommended shelf life for this product is 1 year from date of receipt.

RINZF is a novel member of the Cys2-His2 zinc finger gene family, having a cDNA sequence of 3.8 kilobases. Apart from the Cys2-His2 zinc finger domains, the RIN ZF coding sequence bears little resemblance to other reported zinc finger genes. The amino-terminal region of the protein is an activation domain, despite the lack of recognizable activation motifs, such as homopolymeric glutamine and proline-rich stretches. Instead, it possesses several regions rich in basic residues, often associated with repressor domains. The gene encoding the RINZF protein is mapped on human chromosome 8q13-q21.1. The protein is highly conserved and acts as a transcriptional regulator. The protein competes with Sp1 binding at the CACC cis-regulatory element of the gastrin promoter and thus has a down-regulatory effect on gastrin transcription. The existence of two transcript variants, isoform 1 and 2, produced by alternate splicing of the RINZF gene has been studied.

Specifications

• Antigen: ZBTB10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZBTB10
• Gene Alias: RINZF, zinc finger and BTB domain-containing protein 10, zinc finger protein RIN ZF, zinc finger protein RINZF
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 65986
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q96DT7
• Gene Symbols: ZBTB10
• Immunogen: Between 50 and 100
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG