ZBTB2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A303261A

Catalog No. 50-156-4682

Description

The recommended shelf life for this product is 1 year from date of receipt.

ZBTB2 is a member of the POK (POZ domain Krüppel-like zinc finger) family and plays an important role in cell cycle regulation. It is a transcription factor and a potent repressor of the ARF-HDM2-p53-p21 pathway. ZBTB2 represses the transcription of the p21, p53 and ARF genes and activates HDM2 gene. ZBTB2 and Sp1 compete with each other in binding to the GC-box 5/6 elements and the two p53 binding elements. ZBTB2 directly interacted with p53 via its zinc fingers, inhibiting p53 binding and repressing transcription activation by p53.

Specifications

• Antigen: ZBTB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ZBTB2
• Gene Alias: Zinc finger and BTB domain-containing protein 2; ZNF437; KIAA1483; ZBTB2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57621
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q8N680
• Gene Symbols: ZBTB2
• Immunogen: Between 50 and 100
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG